Searchable abstracts of presentations at key conferences in endocrinology

ea0099p277 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Evaluation of a new prototype ELISA for the detection of autoantibodies against IA2 in patients with type 1 diabetes mellitus

Elleuche Skander , Ho Gia-Gia , Kuhnl Alexander , Baranowska-Dell Malgorzata , Masur Kai , Augstein Petra , Saschenbrecker Sandra , Probst Christian , Komorowski Lars , Dieckmann Kersten , Dahnrich Cornelia

Introduction: Autoantibodies against insulinoma-associated antigen-2 (anti-IA2) are an important marker for diagnosis and prediction of new-onset type 1 diabetes mellitus (T1DM). Here we report on a new prototype Anti-IA2 ELISA with shorter total incubation time (3h15min) compared to the established EUROIMMUN Anti-IA2 ELISA (minimum 17h40min). The study evaluates the performance of the prototype assay.Methods: The clinical performance of the prototype EL...